Curriculum Vitae

Personal Data:

Name & Surname: Seyed Hadi Mousavi

Date & Place of Birth: 23/8/1974 (1/6/1353)  Torbateheydarieh-Iran

Gender: Male

Citizenship: Iranian

Marital Status: Married

Work address: Department of Pharmacology,School ofMedicine, Mashhad University of Medical Sciences,Mashhad,Iran.

Tel :09155199598

E-mail: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید, این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

1-      Current position (August 2006)

1-   Associate Professor, Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2-   Faculty Member of Pharmacological Research Centre of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.

3-   Faculty Member, Medical Toxicology Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.

4-  Research Manager of School of Medicine, Mashhad University of Medical Sciences 

5-  Faculty Member, Education & Development Department, School of Medicine, Mashhad University of Medical Sciences. 

6-  Executive Member of Middle-Eastern Association for Cancer Research  (MEACR).

Academic Background:

1-      May 2006

Receiving Ph.D. degree from the Department of  Pharmacology  at Iran University of Medical Sciences Faculty of Medicine,Tehran,Iran.

2-      July 2005 until  December 2005

Visiting researcher in the laboratory of Dr. Peter. Hersey  atUniversity of Newcastle, Australia.

3-      January 2001

Beginning a Ph.D. program in the Department of  Pharmacology at Iran University of Medical Sciences Faculty of Medicine,Tehran,Iran.

4-      September 1992 until September 2000

Medical Doctor program at Mashhad University of Medical Sciences Faculty of Medicine,Mashhad,Iran.

Awards and Ranks:

2009

First Rank in the “Best Researcher Award” at Mashhad University of Medical Science

2009

Best Idea in Medical education in “Shahid Motahhari Medical Education Festival” at Mashhad University of Medical Sciences

2005
Iranian Ministry of Health and Medical Education research travel grant for a 6‑month stay as part of my Ph.D. program in the laboratory of Dr. P. Hersey  atUniversity of Newcastle, Australia

2000
National Ph.D. Entrance Exam (Pharmacology), 1^st rank among 200 participants.

1998

Third Rank in internship exam at Mashhad University of Medical Sciences.

Membership:

1- Iranian Society of Toxicology, April 2006 to date.

2- Asia Pacific Association of Medical Toxicology, December 2007  to date.

3- Middle-Eastern Association for Cancer Research  (MEACR).

Published Original papers:

2- Sharifi AM, Mousavi SH, Bakhshayesh M, Tehrani FK, Mahmoudian M, Oryan S. Study of correlation between lead-induced cytotoxicity and nitric oxide production in PC12 cells. Toxicol Lett. 2005 Dec 30;160(1):43-8. Epub 2005 Jul 21.

3- Sharifi AM, Mousavi SH, Larijani B. Study of correlation between systolic blood pressure and angiotensin converting enzyme (ACE) activity in STZ induced diabetic rats. Iranian Journal of Diabetes and Lipid Disorders. 2005 4(2): 7-13

4- Sharifi AM, Mousavi SH, Larijani B. Effect of insulin on serum and tissue ACE  activity in diabetic rats. Iranian Journal of Diabetes and Lipid Disorders. 2004 3(2): 195-200

5- Farhadi M, Parivar K, Sharifi AM, Zeinali S, Mousavi SH, Bakhshayesh M. Effect of different glucose concentration on PC12 cells apoptosis: role of Bax and Bcl-2 proteins. Medical Sciences Journal of IslamicAzadUniversity. 2005 15(4), 161-166

6-Fata AM, Bloorsaz M, Mousavi SH.  Porbadakhshan M. Comparison the efficacy of griseofulvin and miconazole (alone and together) on 100 patients suffering from dermatophytosis in Mashhad. Medical Journal ofMashhadUniversity of Medical Sciences  2001, 44 (72), 36-41

7- Mousavi SH^* ,    Zhang XD ,  Sharifi AM  and Hersey P. Study of Rose Bengal-Induced Cell  Death in Melanoma Cells  in the Absence of Light. Iranian Journal of Basic Medical Sciences.  2006. 9 (3), 216-222 

8- Fata AM, Tavasoli F, Mousavi SH, EbrahimBoshra – Al- Amin Sh. Efficacy of  Clotrimazole, Nystatin and Povidone Iodine in Traetment of Patients Suffering from Vaginal Candidiasis. Medical Journal ofMashhadUniversity of Medical Sciences. .. .2007.  (94)

9- Sharifi AM, Mousavi SH, Farhadi M, Larijani B. Study of high glucose-induced apoptosis in PC12 cells: role of bax protein. J Pharmacol Sci. 2007 Jul;104(3):258-62.

10- Mousavi SH^* , and Hersey P. Role  of caspases  and reactive oxygen species in rose bengal-induced toxicity in melanoma cells. Iranian Journal of Basic Medical Sciences. 2007 10 (2), 210-215   

11-  Sharifi AM, Mousavi SH  Studying the Effects of Lead on DNA Fragmentation and Proapoptotic Bax and Antiapoptotic Bcl-2 Protein Expression in PC12 Cells Toxicology Mechanisms and Methods, 2008, 18, 75-79

12- Balali-Mood M, Mousavi SH, Balali-Mood B. Chronic health effects of sulfur mustard  exposure with special reference to Iranian veterans. Emerging Health Threats. 2008, 1:e2, 1-12

13- Mousavi SH^*, Moosavi SH,  Lysosome: as a proposed target for rose bengal in inducing cell death in melanoma cells. Irn J Med Hypotheses Ideas. 2008, 2:12

14.  Alavian SM, Moosavi SH, Mousavi SH, Azizi B, Akbari H, Study of Admission Rate of Hepatitis B Surface Antigen Positive Patients in 50 Dentistry Centers in Tehran(Spring 2003).Hepatitis Monthly 2007; 8(1), 67-69

15- Tavakkol Afshari J, Brook A, Mousavi SH^*. Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines. Food Chem Toxicol, 2008 Nov; 46, 3443-3447.

16 Mousavi SH*, Tayarani-Najaran Z, Hersey P. Apoptosis: from Signalling Pathways to Therapeutic Tools. Iranian Journal of Basic Medical Sciences. Vol. 11, No. 3, Autumn 2008, 121-142                       

17-  Mousavi SH*., Tavakkol Afshari J, Brook A, Jafari Anarkooli I. Direct toxicity of rose bengal in MCF-7 cell line: Role of apoptosis. Food Chem Toxicol, 2009. 47(4):855-9.

18- Mousavi SH*., Tavakkol Afshari J, Brook A, Jafari Anarkooli I. Role of caspases and Bax protein in saffron-induced apoptosis in MCF-7 cells. Food Chem Toxicol, 2009. Aug;47(8):1909-13

19- Mousavi SH*., Tavakkol Afshari J, Brook A. Study of cytotoxic effects of saffron in MCF-7 cells: role of apoptosis. Iranian Journal of Pharmaceutical Sciences (IJPS). 2008: 4(4): 263-268

20- Mousavi SH, Tayarani-Najaran Z, Parsaee H.  Protective effect of saffron extract and crocin on reactive oxygen species-mediated high glucose-induced toxicity in PC12 cells. Cell Mol Neurobiol 2009 Aug 27..   

21- Mousavi SH, Zamani TR SH, Siadat Z, Mahmoudi  M.Study the anti-inflammatory effect of Rose Bengal in LPS-activated macrophages in dark. Journal of Birjand University of Medical Sciences. 2009; 16 (2): 10-17. 

22- Tayarani-Najaran Z, Mousavi SH, Asili J, Emami SA. Growth-inhibitory effect of Scutellaria lindbergii in human cancer cell lines. Food Chem Toxicol. 2009 Nov 20.  

23- Tayarani-Najaran Z, Asili J, Emami SA. Mousavi SH* Analyzing cytotoxic and apoptogenic properties of Scutellaria litwinowii root extract on cancer cell lines. Evidence Based Complementary and Alternative Medicine (Ecam). Dec 2009   

24- Mousavi SH, Tayarani-Najaran Z, Sadeghnia HR. Protective effect of Nigella sativa extract and thymoquinone on serum/glucose deprivation-induced PC12 cells death. Cell Mol Neurobiol. Jan 2010

25- Sharifi AM, Mousavi SH, Jorjani M. Effect of Chronic Lead Exposure on Pro-Apoptotic Bax and Anti-Apoptotic Bcl-2 Protein Expression in Rat Hippocampus In Vivo. Cell Mol Neurobiol. 2010 Feb

26- Tayarani-Najaran, Z, Parsaee H, Hoseini A, Mousavi SH*. Study of noscapine-induced cell death in hepatocellular carcinoma cell line. Pharmacologyonline. Volume 3, September 2009, Pages 522-530

27- Tayarani-Najaran Z, Sadeghnia HR, Asghari M,  Mousavi SH*. Neuroprotective effect of Nigella sativa hydro alcoholic extract on serum/glucose deprivation induced PC12 cells death. Physiology and Pharmacology, 2009, 13 (3), 263 – 270.   

28-  Bakavoli, M. Rahimizadeh, A. Shiri, M. Akbarzadeh, Mousavi SH, Z. Tayarani-Najaran, Z, H. Atapour-Mashhad, M. Nikpour, J. Synthesis of New Derivatives of 3-Aryl-1,5-dimethyl-1H- [1,2,4]triazolo[40,30:1,2]pyrimido[4,5-e][1,3,4]oxadiazines as

Potential  Antiproliferative Agents J. Heterocycl. Chem., 2010,

29- M. Bakavoli, M. Rahimizadeh, A. Shiri, M. Akbarzadeh, Mousavi SH, H. Atapour-Mashhad, Tayarani-Najaran, Z, Synthesis and anticancer evaluation of new derivatives of 3-phenyl-1,5- dimethyl-1H-[1,2,4]triazolo[4’,3’:1,2]pyrimido[4,5-e][1,3,4]oxadiazine J. Chem. Res., 2010, 2010 JULY, 403–406.

30-  Atapour-Mashhad H, Tayarani-Najaran Z,  Davoodnia A, Moloudi R.  Mousavi SH*. Antitumor activity of novel pyrrolo[2,3-d]pyrimidin-4-ones. Drug and Chemical Toxicology, 2011; 34(3): 271–276.

31 Mehri S, Abnous K, Mousavi SH, Shariaty VM, Hosseinzadeh H. Neuroprotective Effect of Crocin on Acrylamide-induced Cytotoxicity in PC12 cells. Cell Mol Neurobiol. 2011 Sep 7

32- Mousavi SH, Moallem SA, Mehri S, Shahsavand S, Nassirli H, Malaekeh-Nikouei B. Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form. Pharm Biol. 2011 Oct;49(10):1039-45.

33- Amir Zamiri-Akhlaghi1, Hasan Rakhshandeh1, Zahra Tayarani-Najaran1, Mousavi SH*. Study of cytotoxic properties of Rosa damascena extract in human cervix carcinoma cell line. Avicenna Journal of Phytomedicine. Vol. 1, No. 2, Autumn 2011, 74-77

34- Tayarani-Najaran Z, Mousavi SH, Vahdati-Mashhadian N, Emami SA, Parsaee H. Scutellaria litwinowii induces apoptosis through both extrinsic and intrinsic apoptotic pathways in human promyelocytic leukemia cells. Nutr Cancer. 2012;64(1):80-8. 2011 Nov 18.

35- Afsharzadeh M, Tayarani-Najaran Z, Zare A, Mousavi SH*. Protective Effect of Scutellaria litwinowii Extract on Serum/Glucose-Deprived Cultured PC12 Cells and Determining the Role of Reactive Oxygen Species. Journal of Toxicology. 2012

36- Tayarani-Najaran Z, Asili J, Parsaee H, Mousavi SH, Vadati Mashhadian N, Mirzaee A, Emami SH. Wogonin and neobaicalein from Scutellaria litwinowii roots are apoptotic for HeLa cells. Rev. Bras. Farmacogn. / Braz. J. Pharmacogn. 2012

37- Rajabi-Mashhadia MT, Mousavi SH, Khosravi-Mashizi MH, ,Ghayour-Mobarhand M, Sahebkard A. Optimum duration of perioperative antibiotics therapy in patients with acute non-perforated appendicitis: a prospective randomized trial. Asian Biomedicine Vol. 6 No. 6 December 2012; 891-894

38- Assessment of Cytotoxic Properties of Safranal and Nanoliposomal Safranal in Various Cancer Cell Lines. Malaeke M,  Mousavi SH,  Shahsavand S, Mehri S, Nassirli H and Moallem SA. Phytotherapy Research 2013

39- Cytotoxic and apoptogenic properties of three isolated diterpenoids from Salvia chorassanica through bioassay-guided fractionation. Tayarani-Najaran Z, Mousavi SH,, Tajfard F, Asili J, Soltani S, Hatamipour M, Emami SA. Food and Chemical Toxicology, 2013

40- Apoptosis Induction of Salvia Chorassanica Root Extract on Human Cervical Cancer Cell Line. Parsaee H, Asili J, Mousavi SH, Soofi H, Emami SA and Tayarani-Najaran Z. Iranian Journal of Pharmaceutical Research (2013), 12 (1): 75-83

41- In vitro evaluation of cytotoxic and apoptogenic properties of Sophora pachycarpa. Tayarani-Najaran Z, Hosseini-Motaez M, Zamiri-Akhlagh A, Emami SA, Mousavi SH*. Iranian Journal of Pharmaceutical Research 2014 Spring;13(2):665-73

42- Acetylcholinesterase Inhibitors Promote Angiogenesis in Chick Chorioallantoic Membrane and Inhibit Apoptosis of Endothelial Cells. Mortazavian SM, Parsaee H, Mousavi SH, Tayarani-Najaran Z, Ghorbani A, Sadeghnia HR. International Journal of Alzheimer's Disease. (2013), Article ID 121068, 7 page

43- Cytotoxic and Apoptotic Potential of Rheum turkestanicum  Janisch Root Extract on Human Cancer and Normal Cells. Shiezadeha F, Mousavi SH, Amiri MS,  Iranshahi M, Tayarani-Najarand  Z,  Karimi G. Iranian Journal of Pharmaceutical Research (2013), 12 (4):

45- Rose Bengal suppresses gastric cancer cell proliferation via apoptosis and inhibits nitric oxide formation in macrophages. Zamani Taghizadeh Rabe S, Mousavi SH, Tabasi N, Rastin M, Siadat Z, Mahmoudi M. Journal of Immunotoxicology. 2014 Feb 27

46- Different effects of adenylyl cyclase activators and phosphodiesterases inhibitors on cervical cancer (HeLa) and breast cancer (MCF-7) cells proliferation.Mahdian D, Shafiee-Nick R, Mousavi SH. Toxicol Mech Methods. 2014 Mar 5.

47- Comparative Studies of Cytotoxic and Apoptotic Properties of Different Extracts and the Essential Oil of Lavandula angustifolia on Malignant and Normal Cells. Tayarani-Najaran Z, Amiri A, Karimi G, Emami SA, Asili J, Mousavi SH*. Nutr Cancer. 2014 Feb 26

48- Saffron in metabolic syndrome: its effects on antibody titers to heat-shock proteins 27, 60, 65 and 70. Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Ghayour-Mobarhan M, Ferns GA.  J Complement Integr Med. 2014 Feb 6;11(1):43-9

49- Viola tricolor Induces Apoptosis in Cancer Cells and Exhibits Antiangiogenic Activity on Chicken Chorioallantoic Membrane. Sadeghnia HR, Ghorbani Hesari T, Mortazavian SM, Mousavi SH, Tayarani-Najaran Z, Ghorbani A. Biomed Res Int. 2014;2014:625792

50- Rhus Coriaria Effect on Serum Uric Acid Level and in Vivo Xanthine Oxidase Activity in Oxonate-Induced Hyperuricemic Mice.  Nazouri Mahdabadi M, Khabjavid Z,Tafakori Baghdarian N, Lookian F, Javid A, Mousavi SH, Hashemy SI. Pharm. Biomed. Sci. 2013 3 (12)J.

51- The role of local renin-angiotensin system on high glucose-induced cell toxicity, apoptosis and reactive oxygen species production in PC12 cells. Iranian Journal of Basic Medical Sciences. 2014

52- Protective Effect of Hibiscus sabdariffa Against Serum/Glucose Deprivation-Induced PC12 Cells Injury., Bakhtiari E, Hosseini A, , Mousavi SH*. Avicenna Journal of Phytomedicine (AJP). 2015 May-Jun;5(3):231-7.

53- In-vitro Evaluation of Cytotoxic and Apoptogenic Properties of Sophora Pachycarpa. Mousavi SH, Motaez M, Zamiri-Akhlaghi A, Emami SA, Tayarani-Najaran Z. Iran J Pharm Res. 2014 Spring;13(2):665-73.

54- Effects of some elicitors on tanshinone production in adventitiousroot cultures of Perovskia abrotanoides Karel. Zaker A, Sykorad C, Gössnitzerd F, Abrishamchi P, Asili J, Mousavi SH, Wawroschd C. Industrial Crops and Products 67 (2015) 97–102

55- Combination of Nigella sativa with Glycyrrhiza glabra and Zingiber officinale augments their protective effects on doxorubicin-induced toxicity in h9c2 cells. Azar Hosseini, Reza Shafiee-Nick, and Mousavi SH. Iran J Basic Med Sci. 2014 Dec; 17(12): 993–1000

56- pyrimidooxadiazine and triazolopyrimidooxadiazine derivatives: synthesis and cytotoxic evaluation in human cancer cell lines. Mousavi SH, Atapour-Mashhad H, Bakavoli M, Shiri A, Akbarzadeh M, Tayarani-Najaran Z.. Bioorg Khim. 2015 Mar-Apr;41(2):227-34

57- Angiotensin II receptor antagonist olmesartan and NF-kappaB inhibitor as cytotoxic and apoptotic agents in MCF-7 human cell line. Bakhtiari E, Hosseini A, Boroushaki MT, Mousavi SH*. J Chemother. 2015 Jul

58-  Effect of saffron on liver metastases in patients suffering from cancers with liver metastases in a randomized, double blind, placebo-controlled clinical trial. Hosseini A, Mousavi SH, Homaei-Shandiz F, Raziee HR, Pezeshki-Rad M, Ghanbari A, Mousavi SH*. AJP

59- Study of crocin & radiotherapy-induced cytotoxicity and apoptosis in the head and neck cancer (HN-5) cell line. Vahid Vazifedan, Javad Sargolzaee, Shokouhozaman Soleymanifard, Azar Fani Pakdel,  Mousavi SH*. IJPR

60- Synergistic, cytotoxic and apoptotic activities of olmesartan with NF-κB inhibitor against HeLa human cell line. Bakhtiari E, Hosseini A, Boroushaki MT, Mousavi SH*. Toxicol Mech Methods. 2015 Sep 2:1-8

61- Saffron supplements modulate serum pro-oxidant-antioxidant balance in patients with metabolic syndrome: A randomized, placebo-controlled clinical trial. Kermani T, Mousavi SH (The first two authors had equal contribution),  Shemshian M, Norouzy A, Mazidi M, Moezzi A, Moghiman T, Ghayour-Mobarhan, M,  Ferns  G. Avicenna J Phytomed, 2015; 5 (5): 427-433.

62- Crocin reduced acrylamide-induced neurotoxicity in Wistar rat through inhibition of oxidative stress. Mehri S; Abnous K; Khooei A; Mousavi SH; Motamed Shariaty V; Hosseinzadeh H. Iran J Basic Med Sci. 2015. 902-908

63- Ctotoxic and apoptogenic effects of Perovskia abrotanoides flower extract on MCF-7 and HeLa cell lines Mohamad Ali Geryani, Davood Mahdian,, Mousavi SH *,Azar Hosseini.  AJP 2016

64- A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. J Complement Integr Med. 2016 Jun 1;13(2):195-9. doi: 10.1515/jcim-2015-0043.

65- Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Mousavi SH, Davari AS, Iranshahi M, Sabouri-Rad S, Tayarani Najaran Z. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.

- Angiotensin II receptor antagonist olmesartan and NF-kappaB inhibitor as cytotoxic and apoptotic agents in MCF-7 human cell line. Bakhtiari E, Hosseini A, Boroushaki MT, Mousavi SH*. J Chemother. 2016 Aug;28(4):314-20

64- Ctotoxic and apoptogenic effects of Perovskia abrotanoides flower extract on MCF-7 and HeLa cell lines. Mohamad Ali Geryani, Davood Mahdian,, Mousavi SH *,Azar Hosseini.  Article 5, Volume 6, Issue 4, June 2016, Page 410-417  

65- A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. J Complement Integr Med. 2016 Jun 1;13(2):195-9. doi: 10.1515/jcim-2015-0043.

66. Capparis spinosa reduces Doxorubicin-induced cardio-toxicity in cardiomyoblast cells. Mousavi SH, Hosseini A, Bakhtiari E, Rakhshandeh H. Avicenna J Phytomed. 2016 Sep-Oct;6(5):488-494.

67. Cytotoxic effects of Urtica dioica radix on human colon (HT29) and gastric (MKN45) cancer cells mediated through oxidative and apoptotic mechanisms. Ghasemi S, Moradzadeh M, Mousavi SH, Sadeghnia HR. Cell Mol Biol (Noisy-le-grand). 2016 Oct 15;62(9):90-96.

68. Protective effect of Viola tricolor and Viola odorata extracts on serum/glucose deprivation-induced neurotoxicity: role of reactive oxygen species. Mousavi SH, Naghizade B, Pourgonabadi S, Ghorbani A. Avicenna J Phytomed. 2016 Jul-Aug;6(4):434-41 

69. Growth inhibition and apoptosis induction by vincetoxicum pumilum Decne. On HL-60 and K562 leukemic cell lines. Najaran, Z.T.,  Mousavi SH.,  Rasoulinejad, M.,  Asili, J.,  Iranshahy, M.,  Emami, S.A. Jundishapur Journal of Natural Pharmaceutical Products Volume 11, Issue 2, 2016, Article number 29370. 

70. Vahid Vazifedan, Seyed Hadi Mousavi * , Javad Sargolzaei  ,  Shokouhozaman Soleymanifard d, and Azar Fani Pakdel. Study of Crocin & Radiotherapy-induced Cytotoxicity and Apoptosis in the Head and Neck Cancer (HN-5) Cell Line. Iranian Journal of Pharmaceutical Research (2017), 16 (1): 230-237

71. Solmaz Pourgonabadi, Mohammad Sadegh Amiri, Seyed Hadi Mousavi*,.Cytotoxic and apoptogenic effects of Bryonia aspera root extract against Hela and HN-5 cancer cell lines . AJP, Vol. 7, No. 1, Jan-Feb 2017

72. Reza Shafiee-Nick, Amir Afshari, Seyed Hadi Mousavi, Abbasali Rafighdoust, Vahid Reza Askari ,Hamid Mollazadeh ,Sahar Fanoudi ,Elmira Mohtashami, Vafa Baradaran Rahimi, Moein Mohebbi, Mohammad Mahdi Vahedi, A comprehensive review on the potential therapeutic benefits of Phosphodiesterase inhibitors on cardiovascular diseases. Biomedicine Pharmacotherapy 94 (2017) 541–556

73.     Tayebe Kermani, Maedeh Zebarjadi, Hassan Mehrad-Majd, Seyed-Reza Mirhafez,  Maryam Shemshian, Faezeh Ghasemi, Elham Mohammadzadeh , Seyed Hadi Mousavi,  Abdolreza Norouzy, Toktam Moghiman, Akram Sadeghi  , Gordon Ferns, Amir Avan,  Elaheh Mahdipour   and Majid Ghayour-Mobarhan* .Anti-inflammatory  effect  of  Crocus  sativus  on  Serum  Cytokine  Levels  in Subjects with Metabolic Syndrome: A Randomized, Double-blind, Placebo-controlled Trial. Current Clinical Pharmacology, 2017;12(2):122-126

74. Bakhtiari E1, Hosseini A2, Mousavi SH*.The role of ROS and NF-κB pathway in olmesartan induced-toxicity in HeLa and mcf-7 cell lines. Biomed Pharmacother. 2017 Sep;93:429-434.

75.  Pourgonabadi, S.a,Mousavi, S.H.,cTayarani-Najaran, Z.d,Ghorbani, A.b. Effect of zoledronate, a third-generation bisphosphonate, on proliferation and apoptosis of human dental pulp stem cells. Canadian Journal of Physiology and PharmacologyVolume 96, Issue 2, 2018, Pages 137-144

76.  Rezvani, M..a,Bakhtiari, E.b,Tayarani-Najaran, Z.d,Mousavi, S.H*e. Synergistic and defensive properties of Emblica officinalis, Terminalia chebula, and Terminalia bellerica extracts against serum/glucose deprivation-induced PC12 cells death. Jundishapur Journal of Natural Pharmaceutical ProductsOpen Access Volume 13, Issue 1, 1 February 2018, Article number e65032.

77.  Mousavi, S,b, Bakhtiari, E.,d, Hosseini, A.b, Jamialahmadi, K.,f. Protective effects of glucosamine and its acetylated derivative on serum/glucose deprivation-induced PC12 cells death: Role of reactive oxygen species. Research in Pharmaceutical Sciences,Volume 13, Issue 2, 1 March 2018, Pages 121-129

78.   Kazemi Oskuee R, Dabbaghi M, Gholami L, Taheri-Bojd S4, Balali-Mood M, Mousavi SH, Malaekeh-Nikouei B. Investigating the influence of polyplex size on toxicity properties of polyethylenimine mediated gene delivery. Life Sci. 2018 Mar 15;197:101-108. doi: 10.1016/j.lfs.2018.02.008. Epub 2018

79.   Solmaz Pourgonabadi, Ahmad Ghorbani, Zahra Tayarani Najarn, Seyed Hadi Mousavi *.In vitro assessment of alendronate toxic and apoptotic effects on human dental pulp stem cells . Iran J Basic Med Sci, Vol. 21, No. 9, Sep 2018

80.   Seyed Hamid Forouzmand  , Seyed Hadi Mousavi, Vahid Vazifedan, Mahnaz Nourbakhsh,   Jamshidkhan Chamani, Azar Hoseini, Azar Fanipakdel * Synergistic effects of Ferula gummosa and radiotherapy on induction of cytotoxicity in HeLa cell line. AJP, Vol. 8, No. 5, Sep-Oct 2018

81.  Vafa Baradaran Rahimi, Vahid Reza Askari, Reza Shirazinia, Sina Soheili-Far, Nafiseh Askari, Pouria Rahmanian-Devin, Zahra Sanei-Far, Seyed Hadi Mousavi, Razieh Ghodsi .Protective effects of hydro-ethanolic extract of Terminalia chebula on primary microglia cells and their polarization (M 1 /M 2 balance). Multiple Sclerosis and Related Disorders 25 (2018) 5–13

82.  Mohammad-Ali Sobhanifara , Baratali Mashkanib , Mohammad Saadatmandzadehc , Hamid Reza Sadeghniad , Seyed Hadi Mousavie*,. Induction of cytotoxicity and apoptosis in FLT3 mutant expressing cells using novel pyrimido cyanoacrylates and quinoline derivatives. Biomedicine & Pharmacotherapy 108 (2018) 893–905

83.  Rahimi VB, Askari VR, Shirazinia R, Soheili-Far S, Askari N, Rahmanian-Devin P, Sanei-Far Z, Mousavi SH, Ghodsi R. Protective effects of hydro-ethanolic extract of Terminalia chebula on primary microglia cells and their polarization (M-1/M-2 balance) Mult Scler Relat Disord. 2018 Oct;25:5-13.

.*  Corresponding  Author

Presentations:         

Mousavi SH^*., Sharifi A.M,  Bakhshayesh M Investigation of lead-induced neurotoxicity  in PC12 cell: Role of Nitric Oxide &  Apoptosis. 6^th annual congress of Asia Pacific Association of Medical Toxicity, Bangkok, Thailand, December 2007.(Oral presentation).

Mousavi SH*, Tavakol Afshari J , Brook A, Jafari I. Study of saffron-induced apoptosis in MCF-7 cells: role of caspase and Bax protein. 4th Life Science postgraduate Conference, 18-20th June 2008, USM, Malaysia (Oral presentation).

Mousavi SH*, Direct toxicity of rose bengal in MCF-7 cell line: Role of apoptosis and Bax protein. 11^th Iranian Pharmaceutical Sciences Conference (IPSC2008)  Kerman, Iran, 18-21 August, 2008. (Oral presentation).

Mousavi SH^*, Shahsavand SH, Mehri  S, Moallem SA,  Malaekeh B. Study of cytotoxic and apoptogenic properties of nano-liposomes forms of crocin compared to crocin in various human cancer cell lines. 11 th    International Conference on Advanced Materials (ICAM). Brazil, September 2009.  (Oral presentation)

Mousavi SH^* Tavakol Afshari J , Brook A.  Saffron: as a promising medicinal plant in breast and cervix cancer treatment. The First International of Gynecology Oncology Congress under the auspices of IGCS.   Mashhad . 10 - 12 Oct. 2008. (Oral presentation)

Mousavi SH^* Tavakol Afshari J , Brook A  Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines. Internatinal sypmosium on saffron a herbal medicinal of 3th millennium. Mashhad. May 2009. (Oral presentation)

Mousavi SH^* Tayarani-Najaran Z,  Atapour-Mashhad H, Davoodnia A, Moloudi R. Cytotoxic and apoptogenic properties of novel pyrrolo[2,3-d]pyrimidin-4-ones in human cancer cell lines. 12^th Iranian Pharmaceutical Sciences Conference (IPSC2010)  Zanjan.Iran, August, 2010. (Oral presentation).

Seyed Hadi Mousavi1*, Faezeh Tajfard², Atefeh Amiri², Farideh Shiezadeh²New medicinal plants as promising antitumor drugs. second annual meeting of the Middle-Eastern Association for Cancer Research (MEACR), November 27 to 29, 2012. . (Oral presentation).

Sharifi AM  Mousavi SH^*., Bakhshayesh Masoomeh . Study  of lead-induced-apoptosis   in PC12 cell. The 9^th Iranian Congress of Toxicology, May 2007,shiraz,Iran

Mousavi SH^*, Tavakol Afshari J, Brook A  Study of cytotoxic and apoptogenic properties of different saffron  extracts in human cancer cells. 6^th annual congress of Asia Pacific Association of Medical Toxicity, Bangkok, Thailand, December 2007

Mousavi SH^*, Parsaee H, Tayrani Z. Study of correlation between glucose-induced cytotoxicity and reactive oxygen species production in pc12 cells. The 10th Iranian Congress of Toxicology, May 2009, Tehran, Iran

Mousavi SH^*, Shahsavand SH, Mehri  S, Moallem SA,  Malaekeh B. Assessment of cytotoxic and apoptogenic properties of safranal and its nanoliposoms in various cancer cell lines. 11 th    International Conference on Advanced Materials (ICAM). Brazil, September 2009.

Davari A, M. Iranshahia, Z. Tayarani-Najaran, S.H. Mousavi*.  Apoptosis induction by auraptene, umbelliprenin and herniarin in MCF-7 cells 12th Iranian Congress of Biochemistry & 4th International Congress  of Biochemistry & Molecular Biology. Mashhad, Iran. 6-9 September 2011.

Seyed Hadi Mousavi*, Mahsa Hossini Motaez, Hojat Soufi, Seyed Ahmad Emami, Zahra Tayarani-Najaran . “Cytotoxic and apoptogenic properties of Sophora pachycarpa and Salvia chorassanica in human cancer cell lines. 10th Scientific Congress of the Asia Pacific Association of Medical Toxicology. November 11-14. 2011

*  Presenting Author

Technical Skills:

Cell culture

Cytotoxicity assay (MTT, WST,…),

Assays of apoptosis & necrosis

 Protein extraction, DNA extraction

Western blotting 

 Flow cytometry:

Assay of mitochondrial membrane potential by flow cytometry

Assay of intracellular reactive oxygen specious (ROS) by flow cytometry

Assay of  cell cycle by flow cytometry

Assay of apoptosis by flow cytometry

HPLC ( Assay of ACE activity)

Assay of Nitric Oxide